A modified peptide shows promise for fighting tumors

A new study from the University of Pennsylvania's School of Veterinary Medicine has shown that a modified peptide, a short chain of amino acids, is a promising new approach to fighting solid tumors. The peptide, a derivative of a naturally occurring peptide called C-type natriuretic peptide (CNP), helps normalize the blood vessels within tumors, which were previously known to be dysfunctional and to promote an immunosuppressive environment. This new treatment not only slowed tumor growth in an animal model but also enhanced the efficacy of multiple therapies, including chemotherapy, radiation, and immunotherapy. This research suggests a new paradigm for cancer treatment, focusing on creating healthy vasculature to reinvigorate the body's anti-tumor immune response rather than simply inhibiting the growth of new blood vessels.

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